Medically reviewed by Dr Sin Yong · Last reviewed · 9 min read
Published 10 October 2026 · Reviewed by Dr Sin Yong

R2T2 is Dr Sin Yong’s name for running his two tone protocols as one plan. R2 Glow uses long-pulsed 755 nm alexandrite and 1064 nm Nd:YAG energy, with the surface left intact, to calm the low-grade inflammation that keeps melanocytes switched on and leaves a background of redness; in Singapore much of that inflammation is driven by daily ultraviolet exposure. T2 Frax Radiance, on the DEKA TORO, clears the pigment already deposited with a 785 nm picosecond pass and adds a longer thermal pulse for a dermal collagen response, which is where its tightening comes from. One works upstream on the driver, the other on the deposit. The balance between them, and whether they run in one session or in sequence, is set at consultation.
T2 Frax Radiance or R2 Glow on their own → · Which brown is yours? →
A brown mark on the face has two parts: the pigment that is already sitting in the skin, and whatever keeps the melanocytes producing more of it. On a Singapore face the second part is usually low-grade inflammation, much of it from year-round ultraviolet exposure, and it shows as a reddish, slightly dull background that makes the whole tone look uneven. Clearing the deposit without calming the driver tends to give a short-lived result; calming the driver without clearing the deposit leaves the fixed marks in place. R2T2 is simply the decision to treat both.
R2 Glow runs long-pulsed 755 nm alexandrite and 1064 nm Nd:YAG energy at parameters chosen for inflammation rather than for pigment, with the epidermis left intact. The 1064 nm wavelength in a long pulse has the longest published record against facial redness: in a series of 66 rosacea patients, long-pulsed Nd:YAG gave good-to-excellent responses in roughly half, with the erythematous subtype responding better than the papulopustular one (Mese Say, J Clin Aesthet Dermatol 2015). Because R2 acts on a process rather than a deposit, its effect accumulates over a course rather than appearing after one pass. Full page: R2 Glow Laser.

T2 Frax Radiance is Dr Sin Yong’s pico laser protocol on the DEKA TORO. Its 785 nm picosecond pulse is over before meaningful heat can spread, so pigment is fragmented by a pressure wave rather than cooked; that photoacoustic mechanism is why picosecond delivery is the safer choice for Fitzpatrick III–V skin, where thermal load risks post-inflammatory hyperpigmentation (Torbeck, Dermatol Surg 2019; Chan, Lasers Surg Med 2016). The second half of the protocol uses the platform’s longer thermal pulse for a dermal collagen response; histology after fractional picosecond treatment shows the small intra-epidermal and dermal injury zones that drive that remodelling (Tanghetti, Lasers Surg Med 2016). That collagen pass is the tightening component of R2T2. Full page: T2 Frax Radiance.

| What the examination shows | Usual order | Why |
|---|---|---|
| Fixed brown marks on calm skin | T2 first, R2 to maintain | The deposit is the main problem; R2 keeps the driver quiet afterwards |
| Reactive, reddish skin with scattered marks | R2 first, T2 once the skin is calmer | Treating pigment over active inflammation raises the PIH risk |
| Both, in roughly equal measure | Same session: R2 pass, then T2 | Different wavelengths and pulse widths, no overlap in target |
| Melasma | R2 Glow or no laser first | Melasma rebounds with heat; picosecond toning only as a conservative adjunct once stable |
| Tanned or recently sun-exposed skin | Wait | More melanin in the epidermis absorbs stray energy |
Transient redness and warmth for hours to a day or two are usual. The specific risk in darker skin types is post-inflammatory hyperpigmentation, which is why the picosecond pass is used for pigment and the thermal pass is kept conservative (Syder, Dermatol Surg 2023). Rebound darkening is the known risk in melasma, which is why melasma is handled differently. Blistering and pale spots are rare and are the reason settings are tested on a small area first. Any blister, open skin, or darkening that spreads should be reported the same day.
Sunscreen every morning, reapplied if outdoors; no exfoliating acids or retinoids for a few days; no sauna, heavy exercise or sun exposure on the day. Make-up can usually be worn the next day. The exact instructions are given in writing after the session.
Whether one or both protocols are needed, how many passes, the area treated, and the number of sessions the examination suggests. Singapore’s healthcare advertising rules do not allow a clinic to publish prices, so the fee is set out in writing after assessment; how fees are quoted explains what moves it.
R2T2 is Dr Sin Yong's combined laser plan: R2 Glow, a non-ablative long-pulsed 755 nm and 1064 nm protocol directed at low-grade inflammation and redness, with T2 Frax Radiance, a 785 nm picosecond pigment pass plus a thermal tightening pass on the DEKA TORO. It is used when a face has both deposited pigment and an inflammatory, reddish background.
It can be, with the R2 pass first and the T2 pass after, because the two use different wavelengths and pulse widths. When the skin is reactive, R2 Glow runs first over a few visits and T2 is added once the skin is calmer. The order is set at consultation.
The T2 half includes a longer thermal pulse for a dermal collagen response, which is where a mild tightening effect comes from. It is a skin-quality effect, not a lift; descended jowls or neck laxity are treated with VF Lift or Time Freeze Laser LCLR®.
Not as a first step. Melasma rebounds with heat, so it usually starts with R2 Glow or no laser at all, and picosecond toning is added only conservatively once it is stable.
The protocol is built for Fitzpatrick III to V. The picosecond pass fragments pigment with a pressure wave rather than heat, which lowers the post-inflammatory hyperpigmentation risk that thermal pigment lasers carry in darker skin. Settings are tested on a small area first, and tanned skin is asked to wait.
The examination decides. R2 Glow works on a process and accumulates over a course; T2 Frax Radiance works on a deposit and the number of passes depends on how much pigment is present. No fixed number is sold in advance.
Torbeck RL, Schilling L, Khorasani H, Dover JS, Arndt KA, Saedi N. Evolution of the picosecond laser: a review of literature. Dermatol Surg. 2019;45(2):183-194. doi:10.1097/DSS.0000000000001697. source
Chan JC, Shek SY, Kono T, Yeung CK, Chan HH. A retrospective analysis on the management of pigmented lesions using a picosecond 755-nm alexandrite laser in Asians. Lasers Surg Med. 2016;48(1):23-29. doi:10.1002/lsm.22443. source
Tanghetti EA. The histology of skin treated with a picosecond alexandrite laser and a fractional lens array. Lasers Surg Med. 2016;48(7):646-652. doi:10.1002/lsm.22540. source
Mese Say E, Okan G, Gökdemir G. Treatment outcomes of long-pulsed Nd:YAG laser for two different subtypes of rosacea (n=66). J Clin Aesthet Dermatol. 2015;8(9):16-20. source
Syder NC, Chen A, Elbuluk N. Radiofrequency microneedling in skin of colour: a review of 35 studies. Dermatol Surg. 2023;49:489. doi:10.1097/DSS.0000000000003733. source
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